Effect of Massage Before or After Exercise on Delayed-Onset Muscle Soreness in a Rat Model

Background: Delayed-onset muscle soreness (DOMS), also known as tenderness of touch, refers to the pain caused by mechanical stimulation, such contraction and stretching. Chinese massage has been widely used in treatment sports fatigue injury, but there is controversy efficacy. In this experiment, we established DOMS model rats observe prevention effect massage, find best time for intervention, provide scientific basis exercise fatigue. Methods: 130 male SD(sprague-dawley, SD) healthy were randomly divided into blank group, control group group. Except other received model. Professionals applied kneading twisting methods on both lower limbs rats. The expression IL-2, IL-6 IL-8 skeletal determined western blot, PCR ELISA, content serum creatine kinase was ELISA. addition, measured concentration Ca2+, Ca2+-ATPase mitochondria muscle. changes structure observed scanning electron microscopy. Results: After IL-6, CK decreased compared with (P < 0.01), post than that front group(P 0.01). Ca2+ 24, 48 72h 24h 0.05). Conclusion: Massage can prevent injury reduce inflammatory reaction after exercise. It improve activity Ca2+-ATPase, enhance transport protect